Ocean Isle Estates (106.0) Real Estate, Homes, Condos for Sale in Key Largo, FL

Experience modern waterfront living at its finest in this exceptional Key Largo residence where striking contemporary design meets the effortless luxury of the Florida Keys. Built in 2023 and spanning 4,787 square feet, this 3-story home offers 6 bedrooms, 5 baths and spectacular water views from nearly every room. Designed for both entertaining and an everyday escape, walls of glass fill the home with natural light while connecting the sophisticated interiors to expansive outdoor living spaces. The resort-style infinity pool features a sun shelf, submerged bar seating and massage jets, all overlooking the water. A rooftop deck and upper terrace capture ocean views, while a covered summer kitchen creates the perfect setting for sunset dinners and entertaining. Boaters will appreciate 70 feet of concrete dockage, a 20,000 pound boat lift and deep-water access that puts the Atlantic in your backyard. Inside, the chef's kitchen and oversized island anchor the open living space, complemented by a dramatic climate-controlled glass wine display. A private theater, versatile game room or gym, and elevator connecting all three levels add another layer of comfort and sophistication. From mornings on the water and endless shades of blue to evenings with breathtaking sunsets, 64 Andros Road offers the ultimate Keys lifestyle: modern, private, sophisticated and designed for those who want to live as beautifully as they play.

64 S Andros Rd, Key Largo

$2,900,000

4 Beds ⋅ 4 Baths ⋅ 621300 MLS

Welcome to Ocean Isle Estates, where luxury living meets the Florida Keys lifestyle. This 4-bedroom, 4-bath concrete home offers a private pool and spa, 70 feet of waterfrontage with deep-water dockage and quick ocean access, an elevator, ocean views, and lush tropical landscaping. Enter through the electric gate to a fully fenced property with covered parking and an inviting entry. Inside, the open main living level features marble flooring, solid wood interior doors, and a custom kitchen with Sub-Zero refrigeration, stainless steel appliances, granite countertops, solid wood cabinetry, a pantry, and a large island. The kitchen, dining, and living areas flow to a generous covered ocean-view balcony, perfect for enjoying the indoor-outdoor Keys lifestyle. Two guest bedrooms with hardwood flooring and a laundry room are located on this level. Upstairs, a second living area with a wet bar opens to another ocean-view balcony. The primary suite offers hardwood flooring, water views, private balcony access, dual walk-in closets, and a spacious bath with dual vanities, an oversized shower, and a jetted tub. A fourth bedroom completes the upper level, with three of the home's four bedrooms offering private en-suite baths. Outdoors, enjoy a private pool and spa surrounded by tropical greenery, creating a secluded, resort-like setting. Boaters, anglers, and divers will appreciate the wide canal, concrete dock, davits, and quick access to world-class fishing and diving. Additional features include solid concrete construction, a metal roof, impact windows and doors, and added privacy with no direct neighbor across the street. Conveniently located less than an hour from Miami, Ocean Isle Estates also offers two waterfront restaurants within the neighborhood. Call today!

52 S Andros Rd, Key Largo

$298,000

621160 MLS

Large 8,378 sf lot. Tier III, Not Hammock, cleared lot in ROGO. X Zone Lot - no flood zone. Approved plans for 3 Bd, 2.5 Bath with one car garage. Partial permit fees paid. Room for pool, parking available for trailer and multiple cars. Garden Cove Marina at walking distance. Close to Gilberts, Buzzards Roost and Buttonwood Grill restaurants. One hour from MIA airport. Owner is also Broker,

2 S Andros Rd Unit N/A, Key Largo

$665,000

3 Beds ⋅ 2 Baths ⋅ 619985 MLS

Located in the highly sought-after Ocean Isle Estates in Key Largo, this beautifully maintained 3-bedroom, 2-bath home combines comfort, functionality, and the best of Keys living. Inside, you'll find a spacious dining area and an open concept kitchen that flows seamlessly into the main living spaces, making the home ideal for both everyday living and entertaining. The AC system was replaced Dec 2025, adding to the home's overall efficiency and peace of mind. Additional upgrades include hurricane impact windows and doors, a durable metal roof, and desirable X-zone elevation with no worries about flooding. Step outside to a fully fenced yard that is beautifully landscaped and enhanced with custom outdoor lighting, creating an inviting outdoor setting perfect for relaxing or hosting guests. There is ample parking for multiple vehicles, boats, and even an RV. Ideally situated for an easy commute to Miami while still enjoying the relaxed Florida Keys lifestyle, this property is a fantastic opportunity for a full-time residence, weekend retreat, or investment property.

8 N End Rd, Key Largo

$698,000

2 Beds ⋅ 2 Baths ⋅ 619981 MLS

X Flood Zone, Concrete home on TWO fenced lots with a Garage !! Ground level home with a newer ( 2018) metal roof on High elevation. Updated kitchen with wood cabinetry and stainless steel appliances. 12,000sq.ft. lot with storage and secured rolling gate entrance, plenty of boat trailer storage, parking and room for a pool. Close to Buzzards Roost restaurant and Garden Cove Marina where they have racks for boats with in & out service & fuel.

8 S Andros Rd, Key Largo

$665,000

3 Beds ⋅ 2 Baths ⋅ 619960 MLS

Welcome to island living in beautiful Key Largo! This well-cared-for 3-bedroom, 2-bath home offers the perfect combination of comfort, outdoor enjoyment, and the laid-back Florida Keys lifestyle. Thoughtfully updated over the years, the home features impact windows and doors for added protection and peace of mind. The kitchen was beautifully renovated in 2021, while the bathroom was updated in July 2023. Stainless steel appliances were installed in 2015, along with a new water heater. The air conditioning system was replaced in 2020, and the washer and dryer were updated in 2025. Outdoor living truly shines here. The spacious deck and tiki hut were built in 2018, creating an ideal setting for entertaining or relaxing after a day on the water. The tiki hut was freshly re-thatched in May 2026, and the hot tub, purchased in 2018, received a new filter motor in 2021. Situated on a 6,000 sq. ft. lot with nearly 1,300 sq. ft. under air, this tropical retreat is just steps from a marina and popular local favorites including Buzzard's Roost and Shipwreck's Bar & Grill. Enjoy everything Key Largo has to offer, from world-class fishing, diving, and boating to waterfront dining, shopping, and nearby parks filled with natural beauty and marine life. Whether you are searching for a full-time residence, vacation getaway, or investment opportunity, this property captures the essence of the Florida Keys lifestyle. Schedule your private showing today and experience your own piece of paradise!

32 S Andros Rd, Key Largo

$900,000

3 Beds ⋅ 3 Baths ⋅ 618886 MLS

Luxurious custom built home constructed by the owner himself. This two story home is equipped with impact windows and doors. The upstairs includes 3 bedrooms and 2 full bathrooms. Master suite boasts a walk in closet, en-suite w/ double sinks & vanities and bidet. Downstairs also offers a custom kitchen equipped with all G/E appliances, 3 door refrigerator, wine cooler, wood cabinetry, granite counter tops and an island located right in the center. Also located on the bottom floor is a spacious living room, dining room, laundry room and full bathroom. This home also offers tray ceilings and crown moulding throughout, pavers, and 2 ample upstair porches. Only an hour drive to Miami and you can keep your boat at the Garden Cove Marina with direct ocean access.

27 Abaco Rd, Key Largo

$499,999

616762 MLS

Three (Commercial) adjacent lots available for sale together (1,500,000 Dollars) Ideally located on the famous US1 (Overseas Hwy) in Key Largo. Zoning is being changed to Commercial as previously zoned in the 90's, offering endless possibilities for your business. The property already has water and sewer in place, making it ready for immediate development. With exceptional exposure along this high-traffic corridor, this is a rare opportunity to build a one-of-a-kind commercial space in one of the most desirable locations in the Florida Keys. Don't miss out on securing this prime property for your future success! (3 Lots 18,19,20 must be sold at the same time.)

106261 Overseas Hwy Unit LOT 20, Key Largo

$2,100,000

4 Beds ⋅ 3 Baths ⋅ 617928 MLS

Your Dream Waterfront Oasis Awaits! Welcome to this extraordinary custom-built waterfront home located on Exuma Rd in the serene Ocean Isle Estates. This stunning residence harmoniously combines luxury and comfort, perfectly poised to embrace the refreshing ocean breezes and breathtaking water views all year round. As you step through the grand entrance, you'll be greeted by a spacious garage and an inviting first-floor guest suite, complete with its own private screened-in porch—ideal for morning coffee or evening relaxation. Take a leisurely stroll through the elegant pass-through to the poolside area and spa, where you can unwind and soak up the sun. Ascend the exquisite interior marble staircase, adorned with a unique rock-lined wall that leads you to the heart of the home—the magnificent great room. Here, you'll be captivated by the meticulous attention to detail, featuring tray ceilings, crown molding, and stunning travertine marble that elevate every corner of this residence. The gourmet kitchen is a chef's delight, boasting custom hardwood cabinets, stylish lighting, a wine chiller, luxurious granite countertops, and top-of-the-line stainless steel appliances. It's a perfect setting for preparing culinary masterpieces or entertaining friends and family. With direct and easy access to the ocean, your aquatic adventures are just steps away! Enjoy the tranquility of the neighborhood, with a fantastic local restaurant and marina just a stone's throw from your doorstep. This home is conveniently located near Miami, making it an ideal retreat while remaining close to the vibrant '''keys life''. Don't miss this incredible opportunity to own a slice of paradise at an unbeatable price! Schedule your private tour today and feel the magic of waterfront living!

10 S Exuma Rd, Key Largo

$936,000

3 Beds ⋅ 3 Baths ⋅ 616939 MLS

NEWLY BUILT HOME! Spacious 3 bedrooms and 3 full baths conveniently located in Garden Cove Key Largo.. With 2,790 square feet of living area this home features expansive living areas rarely found at this price point. Contemporary design features an open floor plan with room for the whole family. The designer kitchen includes all stainless appliances with quartz counter tops and under cabinet lighting. This solidly built home is engineered to resist 170 MPH wind with impact windows & doors and a metal roof. With easy access to all Key Largo has to offer and only a short drive to the mainland this convenient location will make living here easy.

25 Abaco Rd, Key Largo

$600,000

2 Beds ⋅ 2 Baths ⋅ 609779 MLS

For Statistical Purposes only

14 Abaco Rd, Key Largo

$975,000

5 Beds ⋅ 3 Baths ⋅ 613098 MLS

13 Garden Cove Dr, Key Largo

$500,000

611329 MLS

Cleared and fenced waterfront lot, in desirable Ocean Isle Estates in Key Largo, FL, with direct ocean access. This lot is oversized, boasting 10,500 square feet! Concrete dock is in beautiful condition and is 30 feet long, located on the large turning basin. This is a Tier 3 (build-able) lot and is ready for you to submit your building plans to Monroe County. This location affords fast ocean access, where you can be on the reefs in minutes, from your dock! Like the Bay? There is also fast bay access, via South Creek and the Adams Cut Waterway. Like flats fishing? Bonefish and Tarpon are abundant on the east side of Radabob Key, just moments from your dock. Notable neighborhood features include the Buzzards Roost Restaurant, Garden Cove Marina and Shipwrecks Pub. Your dream home site awaits. Call today, for more information

00 Cayman Ln, Key Largo

$899,000

5 Beds ⋅ 3 Baths ⋅ 610985 MLS

Price reduced because seller is relocating! Rare 5 bedroom Key Largo residence with 3/2 upstairs and 2/1 down. Nice, modern finishes complement this all concrete, turn-key 2021 home located in North Key Largo. Dining and full service marina right around the corner, close to Dagney Johnson Botanical State Park.

19 N End Rd, Key Largo

$718,000

3 Beds ⋅ 2 Baths ⋅ 615153 MLS

This Concrete home with metal roof comes practically turnkey ready for your immediate enjoyment; it has been so well maintained. Featuring 2 bed / 1 bath upstairs and a separate 1 bed / 1 bath downstairs. All safe and secure legally above flood with impact windows and doors. The outdoor space of this home is full of entertainment and enjoyment with Screened in porches all around, a Gated yard with PVC privacy fencing, a back yard Gazebo, a ready to jump in the steel frame pool and a gorgeous stone outdoor shower! The seller boasts that this home is surrounded by Nature, privacy and amazing neighbors. Just a short distance away from phenomenal restaurants and a boat marina and county beach just down the street. The Best part is there are NO HOA's here!

15 Garden Cove Dr, Key Largo

$900,000

614575 MLS

Exceptional Oceanfront Opportunity in Ocean Isle Estates Discover one of the last remaining vacant lots in the prestigious Ocean Isle Estates, offering a rare chance to build your dream home in an idyllic location with direct ocean access. This expansive 8,400 sq ft lot boasts 70 ft of stunning waterfront, complete with a cut coral seawall, ensuring both beauty and functionality. Enjoy unparalleled privacy with a solid wall on the east side and secure fencing on the west, making this property a serene retreat. With its prime location, you'll be just moments away from the best that coastal living has to offer. While no plans or permits are in place, the possibilities are endless for those ready to create a personalized oasis by the sea. Don't miss your opportunity to invest in this prime piece of real estate and embrace the coastal lifestyle you've always dreamed of! Seize the opportunity - your waterfront paradise awaits!

8 S Exuma Rd, Key Largo

$580,000

3 Beds ⋅ 2 Baths ⋅ 607268 MLS

Diamond in the Rough - Waiting for your Finishing Touch! This Concrete Bunker features 3 bedrooms & 2 baths, concrete block construction, open concept living, large lot and located in the X-zone, (highest elevation in the Keys = no or low flood insurance). New roof in 2021. Convenient location close to elementary/middle school, the College of the Florida Keys, shopping, and restaurants. PLUS super easy commute to Ocean Reef and the mainland. Nearby you'll find Buzzards Roost Bar & Grill, Shipwreck's Bar & Grill, Garden Cove Marina, and Dagny Johnson Park. Land across the street owned by the State means no homes and lots of privacy. Plenty of parking for all your cars and toys. Opportunity is Knocking, Open the Door!!!

11 Garden Cove Dr, Key Largo

$499,999

616761 MLS

Three (Commercial) adjacent lots available for sale together (1,500,000 dollars) Ideally located on the famous US1 (Overseas Hwy) in Key Largo. Zoning is being changed to Commercial as previously zoned in the 90's, offering endless possibilities for your business. The property already has water and sewer in place, making it ready for immediate development. With exceptional exposure along this high-traffic corridor, this is a rare opportunity to build a one-of-a-kind commercial space in one of the most desirable locations in the Florida Keys. Don't miss out on securing this prime property for your future success! (3 Lots 18,19,20 must be sold at the same time.)

106281 Overseas Hwy Unit Lot 19, Key Largo

$650,000

3 Beds ⋅ 2 Baths ⋅ 617039 MLS

Priced to sell quickly, this is a 3-bedroom, 2 full bath CBS (concrete) 1,500sq' home, on a huge ¼ acre lot in Ocean Isle Estates, Key Largo! Huge side lot with space for RV, Boats, Trailers and even a pool! With a separate Livingroom in the front of the house with a huge separate dining room/living area off the open concept kitchen offers lots of space. Large master living room with ensuite bathroom of the dining room. Two separate bedrooms with a Jack and Jill bathroom off the living room. Separate laundry room/pantry off the kitchen. Needs TLC but what incredible potential! Ground level, high elevation (Zone X), right down the street from Buzzards Roost restaurant and Bar and Garden Cove Marina with in-out boat storage with fuel. Tons of space for boats, trailers, RV's and more! One of the first houses in the Keys! Makes easy access to Miami or Ocean Reef Club. Monroe County property appraiser reflects 2025 fair market value is $647,224. Renter is leaving by December 1st. More photos to come. Sold 'As IS'. Needs TLC and the side lot is becoming overgrown.

1 N End Rd, Key Largo

$1,500,000

2 Beds ⋅ 2 Baths ⋅ 613759 MLS

A wonderful opportunity in the fabulous Florida Keys! This comfortable home features a relaxed tropical setting of mature landscaping and ocean breezes. The very rare private 10-foot-wide ramp makes it easy to launch your Kayaks, paddleboards, or small boat to explore the natural beauty of John Pennekamp State Park located right behind your home. The 60-foot dock is located on an expansive 85-foot wide, deep-water canal where maneuvering a large boat is a breeze. The homes solid construction includes a concrete roof for peace of mind and lower insurance rates. Loads of covered parking and an attached garage plus an exterior elevator make everyday living very convenient. The interior of this charming home includes a bonus area that can be a den, loft, or office with great views and roof access. The home is within easy walking distance of some of Key Largos best restaurants and Bars. All of this is just 40 minutes to the mainland making the commute to your island paradise very easy.

25 S Exuma Rd, Key Largo

$2,595,000

5 Beds ⋅ 5 Baths ⋅ 612685 MLS

Waterfront home with deep canal and direct Atlantic Ocean access that features a new metal roof, 2 new A/C's, new paint, water heaters, etc. This home can be used as a 2 bed/ 2 bath downstairs and a 3 bed / 3 bath upstairs with separate entrances to both living areas or as a 5 bed / 5 bath combined home. The property can be used as a split rental and has a 5 star rating through VRBO with over 25 + reviews so it's a great investment opportunity. The oversized pool and jacuzzi are heated with a fully permitted outdoor Tiki hut and kitchen area which is fully fenced. The 70' wide concrete deep water dock has a 20,000 elevator lift and 11,000lb davits for your boats or jet skis. Pennekamp Park with great fishing and diving. Furnishings available. .

23 S Exuma Rd, Key Largo

$499,999

616760 MLS

Three (Commercial) adjacent lots available for sale together (1,500,000 dollars) Ideally located on the famous US1 (Overseas Hwy) in Key Largo. Zoning is being changed to Commercial as previously zoned in the 90's, offering endless possibilities for your business. The property already has water and sewer in place, making it ready for immediate development. With exceptional exposure along this high-traffic corridor, this is a rare opportunity to build a one-of-a-kind commercial space in one of the most desirable locations in the Florida Keys. Don't miss out on securing this prime property for your future success! (3 Lots 18,19,20 must be sold at the same time.)

106281 Overseas Hwy Unit LOT 18, Key Largo

$790,000

3 Beds ⋅ 2 Baths ⋅ 610423 MLS

Custom built CBS 3-bedroom, 2-bath home offers everything you need for comfortable living. Enjoy the luxury of a 2-car air-conditioned garage with durable epoxy floors. The fenced backyard provides privacy and a safe space for outdoor activities. Located in a great neighborhood, this home offers easy access to Miami and is conveniently situated near fantastic restaurants. There's plenty of space for parking boats and RVs, and a nearby marina offers dry storage with in-and-out service. Don't miss out on this perfect blend of comfort and convenience!

14 N End Rd, Key Largo

$10,999,999

6 Beds ⋅ 6 Baths ⋅ 617713 MLS

Introducing 57 Garden Cove Drive, a rare opportunity to own a private, resort-style Key Largo waterfront compound set on nearly 26,000 square feet of land, now OFFERED TOGETHER with an additional adjacent vacant residential parcel, creating exceptional flexibility for future expansion or development. Thoughtfully designed to capture both scale and functionality, the residence features 6 bedrooms & 6 bathrooms, complemented by a private elevator for seamless access throughout. Expansive interiors are filled with natural light, effortlessly connecting indoor living spaces to the surrounding tropical landscape. For boating enthusiasts, the property offers 100FT of premium dockage delivering immediate & unrestricted access to open water -- a rare & highly desirable feature in the Keys. Beyond its lifestyle appeal, the property stands out as a proven income-producing asset. With 7-day short-term rental approval, it is currently operating as a successful vacation rental and wedding venue, supported by an exceptional rental history -- offering both immediate revenue & long-term investment potential. The true differentiator lies in the land and flexibility. With the inclusion of the adjacent parcel, the property presents a unique opportunity to further enhance the estate -- whether through additional structures, expanded amenities, or the creation of a fully realized private resort-style compound. Framed by swaying palms & open water views, this is more than a home -- it is a turnkey lifestyle investment with development upside, positioned in one of the most desirable waterfront enclaves in the Florida Keys.

57 Garden Cove Dr, Key Largo

$3,850,000

5 Beds ⋅ 5 Baths ⋅ 612971 MLS

Boater's Paradise in Key Largo: Where the Atlantic meets luxury living, this three-story waterfront retreat offers the quintessential Keys lifestyle you've been dreaming of. 70 feet of prime dockage and dual boat lifts (20K & 10K), your nautical adventures begins at your doorstep. Spanning three meticulously designed levels, this exceptional residence maximizes its oceanfront setting. The crown jewel is the top floor entertainment space, where a chef's kitchen flows seamlessly into an open-concept living area. Here, the Atlantic Ocean becomes your living room's backdrop, with sweeping views that transform each sunrise into a daily celebration. Five generous bedrooms feature walk-out balconies through impact sliding glass doors, treating you to panoramic views of both the Atlantic Ocean and serene Rattlesnake Creek. The 360-degree perspectives remind you that water truly is way of life here. Luxury meets convenience with thoughtful amenities including: An elevator serving all three floors, refreshing pool and hot tub, 70 feet of protected dockage Dual boat lifts, Impact windows, 4.5 well-appointed bathrooms. The location strikes the perfect balance between accessibility and escape. Positioned just off the Stretch in Key Largo. Walk to local restaurants for fresh catch of the day, or lose yourself in the natural beauty of nearby Dagny Johnson State Park. This isn't just a home - it's your gateway to the Florida Keys lifestyle, where every day feels like a vacation and the ocean is always calling.

66 S Andros Rd, Key Largo

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Ocean Isle Estates (106.0) Real Estate & Homes